ea0032s16.1 | Oncogenic signals in thyroid cancer - therapeutic prospects | ECE2013
Charles Roch-Philippe
, Silva Jilian
, Iezza Gioia
, Phillips Wayne A
, McMahon Martin
Thyroid malignancies are the most common type of endocrine tumors. Of the various histological sub-types, anaplastic thyroid carcinoma (ATC) represents 2% of all cases but is responsible for most of the thyroid cancer related death.Indeed, ATC is regarded as one of the more aggressive and hard to treat forms of human cancer. Moreover, to date, there is a paucity of relevant models to study how the signature genetic abnormalities detected in ATC contribut...